Jason McLellan is a professor of molecular biosciences and the Welch Chair in Chemistry at The University of Texas at Austin. He researches viral and bacterial proteins, and his work to understand how these proteins are structured and how they function has factored into the development of vaccines and potential treatments for deadly pathogens ...

Jason S. McLellan is a structural biologist, professor in the Department of Molecular Biosciences and Robert A. Welch Chair in Chemistry at The University of Texas at Austin [1] who specializes in understanding the structure and function of viral proteins, including those of coronaviruses. [2]

Structural biologist Jason McLellan and immunologist Barney Graham used structure-based vaccine design to stabilize and modify surface proteins of viruses. Their work contributed to the development of COVID-19 vaccines, and since 2020, billions of doses of these vaccines have been administered globally.

Jason S. McLellan. Professor of Molecular Biosciences. Verified email at austin.utexas.edu - Homepage. structural biology virology biophysics vaccines. Articles Cited by Public access. Title. Sort. Sort by citations Sort by year Sort by title. Cited by. Cited by. Year; Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.

Jason S. McLellan, Professor of Molecular Biosciences Robert A. Welch Chair in Chemistry. Jason earned a BS in chemistry with an emphasis in biochemistry from Wayne State University in Detroit, Michigan. Afterward, he obtained his PhD from the Johns Hopkins University School of Medicine in Baltimore, Maryland in the laboratory of Dr. Daniel Leahy.

Jason S. McLellan specializes in understanding the structure and function of viral proteins, including those of coronaviruses. His research focuses on applying structural information to the rational design of vaccines and other therapies for viruses, including SARS-CoV-2, the novel coronavirus that causes COVID-19.

Chemistry Alumnus Jason McLellan '03 has been inducted into the National Inventors Hall of Fame for his work using structure-based vaccine design to stabilize and modify surface proteins of viruses. A structural biologist, McLellan and immunologist and virologist Barney Graham have led discoveries that contributed to the development of the COVID-19 and respiratory syncytial virus (RSV) vaccines.

Jan 16, 2025 · AUSTIN, Texas — Jason McLellan, professor in the Department of Molecular Biosciences and Robert A. Welch Chair in Chemistry at The University of Texas at Austin, has been selected for induction into the National Inventors Hall of Fame for his work on structure-based vaccine design that led to the development of vaccines to fight COVID-19 and ...

Apr 7, 2023 · Jason McLellan, the Welch Chair in Chemistry and a professor in the Department of Molecular Biosciences, was recently honored at a ceremony with the award. He and his research team figured out how to produce a stable version of the coronavirus spike protein used to develop the leading COVID-19 vaccines.

We seek to obtain structural information on these proteins and their interactions with host macromolecules and translate this knowledge into the rational development of therapeutic interventions such as small-molecule inhibitors, protective antibodies and …