GEN3d
Dysfunctional Mitochondria Trigger Retrograde Signaling that Impairs Pancreatic β-Cells
Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...
Biochemists discover self-repair function in key photosynthetic protein complex
Cyanobacteria began contributing oxygen to Earth's mostly noxious atmosphere more than 2 billion years ago. The photosystem ...
BioWorld9d
Study HINTs at new target for acute pancreatitis
Acute pancreatitis (AP) is a gastrointestinal disorder characterized by inflammation and necrosis of the pancreatic acinar cells. Mitochondrial homeostasis is key to energy metabolism and redox ...
BioWorld21d
DAP3 gene behind Perrault syndrome, study finds
Mitoribosomes are present in the mitochondria of all eukaryotic cells. Their function is to allow the translation of mitochondrial mRNA that exclusively encodes components of the oxidative ...
Business Wire23d
BPGbio Unveils Research on the Identification of Novel Pancreatic Cancer Patient Subtypes at ASCO GI 2025 Paving the Way for Tailored Treatment
BOSTON--(BUSINESS WIRE)--BPGbio, Inc., a leading biology-first, AI-powered clinical-stage biopharma company focused on mitochondrial biology and protein homeostasis, today announced the ...
Frontiers26d
Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts’ blood cells in space
Figure 2. Top 50 canonical pathways identified by IPA. As shown in Figure 2, among the top dysregulated pathways are mitochondria dysfunction and oxidative phosphorylation. These pathways are ...
Frontiers26d
Mitochondrial abnormalities as a target of intervention in acute myeloid leukemia
However, the profound metabolic changes to mitochondria also render these organelles more sensitive to damage and place them precariously close to excess mitophagic activation. This review discusses ...
C&EN28d
Strong and Fireproof Regenerated Wood via a Combined Phosphorylation-Surface Nanofibrillation and Ionic Cross-Linking Strategy
Department of Chemistry, New Cornerstone Science Laboratory, Institute of Biomimetic Materials & Chemistry, Anhui Engineering Laboratory of Biomimetic Materials, Division of Nanomaterials & Chemistry, ...