We hypothesized that inhibition of IGF-I receptor expression in the psoriasis lesion would reverse psoriatic epidermal hyperplasia by slowing the rate of keratinocyte cell division. Here we report ...

INNOVENT BIO (01801.HK)'s total product revenue for 2024 amounted to more than RMB8.2 billion, representing a robust YoY growth of over 40%, according to INNOVENT BIO's announcement. In 4Q24, the ...

Anxiety disorders, characterized by an excessive apprehension about real or perceived threats and dysfunctional behaviors aimed at avoiding these threats, are among the most common mental health ...

Linsitinib is an oral small molecule that inhibits the activity of insulin-like growth factor-1 receptor (IGF-1R). It is believed that inhibition of IGF-1R may help reduce orbital inflammation and ...

However, with the anti-IGF-1R antibody Tepezza showing the benefits of targeting the receptor in TED, Sling spied a chance to use linsitinib in the eye disease. The biotech launched with $35 ...

Topline results were announced from a phase 2/3 trial evaluating linsitinib for the treatment of moderate to severe thyroid eye disease.

Linsitinib, which is designed to inhibit the insulin-like growth factor-1 receptor (IGF-1R) target, has an established safety profile in 15 clinical trials in multiple disease areas in more than ...

hGH exerts its effects through target cells by binding to specific membrane receptors found in abundance throughout the body. 13 It has both direct and indirect effects on the tissues; the indirect ...

Viridian Therapeutics, Inc. (NASDAQ:VRDN – Get Free Report) has earned an average recommendation of “Moderate Buy” from the twelve research firms that are currently covering the company, Ratings ...