GLUT1 is the most abundantly expressed glucose transporter in chondrocytes. Objectives: In this study, we examined the impact of GLUT1 inhibition on cartilage and chondrocyte metabolism in a murine ...

Braizon’s technology is the first to not only successfully manipulate the glucose transporter GLUT1 — the brain’s primary energy pathway — but also to deliver substantial quantities of ...

In previous studies, Richard Wang, MD, PhD, and his team were surprised to discover that normal skin cells don’t need GLUT1 when they are developing. This finding led them to wonder if stopping the ...

Objectives Glucose is a major source to fuel the growth of cancer. Higher utilization of glucose also correlates with overexpression of GLUT-1 transporter in several types of cancer. F-18 labeled ...

Suls A, Dedeken P, Goffin K, Van Esch H, Dupont P. Paroxysmal exercise-induced dyskinesia and epilepsy is due to mutations in SLC2A1, endoding the glucose transporter GLUT1. Brain 2008;131:1831–1844.

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

This important work identifies a non-autophagic role for ATG5 in lysosomal repair and the trafficking of the glucose transporter GLUT1 to the cell surface, mediated through the retromer complex. The ...

Then, the role of aerobic glycolysis in IL-1β production was evaluated, as well in vitro as in vivo using 18 F-fluorodeoxyglucose positron emission tomography imaging and glucose uptake assay, and ...