Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the insulin ...

This important study shows that the activity of hypothalamic hypocretin/orexin neurons (HONs) correlates with body movement over multiple behaviors. Sophisticated techniques and analyses showcase this ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This ...

It is well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is ...

Insulin allows cells to absorb and use glucose. In people with insulin resistance, the cells are unable to use insulin effectively. Insulin resistance occurs when cells in the body do not respond ...

This can lead to stomach problems and pain. Diabetes is a chronic condition in which the body either doesn’t make enough insulin (a hormone that allows cells to take in glucose from the blood) or ...

"They had been there for an extended period of time," police said. Human remains that had been decomposing “for an extended period of time” have been discovered just off of a public hiking ...

Can Jessie's hacks help reverse Sophie's diabetes? Will an overhaul of Aaron's snacking habits help to improve his skin and his confidence?