Pancreatic blood vessel cell map reveals potential diabetes treatment pathways
The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...
Bioengineers Create “Smart Cells” That Detect and Fight Disease in Real-Time
Rice lab pioneers an assembly kit for synthetic sense-and-respond circuits in human cells. Rice University bioengineers have ...
Nature5d
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
Cell death is achieved by two fundamentally different mechanisms: apoptosis and necrosis. Apoptosis is dependent on caspase activation, whereas the caspase-independent necrotic signaling pathway ...
eLife8d
Single-cell sequencing provides clues about the developmental genetic basis of evolutionary adaptations in syngnathid fishes
This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...
eLife12d
Molecular Feature-Based Classification of Retroperitoneal Liposarcoma: A Prospective Cohort Study
Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory for Digestive Health, National Clinical Research Center for Digestive Disease, Beijing ...
Study Finds14d
Desert plant shows promise as colorectal cancer treatment
A common aromatic shrub that has served as traditional medicine for centuries could point the way toward innovative treatments for colorectal cancer ...
TV Sports Markets23d
ICC back in the market for new Pathway rights cycle
The International Cricket Council (ICC) has gone to market with an array of production, media distribution, betting and sponsorship rights to its cycle of ‘Pathway’ events between 2025 and 2027.
C&EN27d
Supramolecular Combination Chemotherapy: Directly Inducing Immunogenic Cell Death To Inhibit Tumor Metastasis via Host–Guest Interactions
Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, P. R. China Laboratory for Clinical Medicine, Capital Medical University, Beijing ...
The New England Journal of Medicine28d
KRAS Oncoprotein Signaling in Cancer
According to this model, mutant KRAS is able to hydrolyze guanosine triphosphate (GTP) and cycle ... effector pathway in pancreatic ductal adenocarcinoma (PDAC) models, with its signaling ...
Scientific Research Publishing29d
Dang, F., Nie, L. and Wei, W. (2020) Ubiquitin Signaling in Cell Cycle Control and Tumorigenesis. Cell Death & Differentiation, 28, 427-438.
This review explores the multifaceted functions of GSPT2, highlighting its involvement in cell cycle regulation and signaling pathways, as well as its potential as a tumor biomarker. By analyzing the ...