A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously ...

Immunotherapy, which uses programmed immune cells to selectively destroy cancer cells, has transformed cancer treatment.

The authors liken the method to the moment just before water reaches 212°F (100°C), when it's neither truly liquid nor truly ...

Senescent cells, or ‘zombie’ cells, are damaged cancer cells that remain active, making it harder to treat tumors.

Chemoradiation with platinum-based chemo is standard for locally advanced cervical cancer, but adverse events drive ...

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

Scientists uncover an enzyme that boosts cancer cell metabolism to fuel growth. The enzyme, GUK1, supports metabolism in cancer cells to help tumors grow.

"We have discovered a molecular switch that can revert the fate of cancer cells," said biologist Kwang-Hyun Cho.