Gene modification can encourage T cell growth, improving cancer treatment's success rate
Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...
technologynetworks2d
Gene Modification Could Improve Immune Cells’ Ability To Combat Cancer
A new study reveals that modifying the CUL5 gene enhances CAR-T cell therapy for leukemia and lymphoma. This improves cell ...
Science Daily11h
Gene modification could improve cancer treatment's success rate
A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...
News Medical on MSN6d
How olive oil bioactives regulate genes linked to insulin resistance
Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...
GEN1d
Dysfunctional Mitochondria Trigger Retrograde Signaling that Impairs Pancreatic β-Cells
Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...
Pancreatic blood vessel cell map reveals potential diabetes treatment pathways
The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...
Nature5d
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
RIP requires its own kinase activity for death signaling. Thus, Fas, TRAIL and TNF receptors can initiate cell death by two alternative pathways, one relying on caspase-8 and the other dependent ...
GEN4h
Macrophages in Newborn, But Not Adult, Mice Help Regenerate Heart Tissue
Understanding why newborns, but not adults, can regenerate the heart could lead to treatments that "reprogram" adult macrophages.
eLife6d
Spatial confinement induces reciprocating migration of epidermal keratinocytes and forms triphasic epithelia
In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...