News Medical on MSN6d
New study reveals how anticancer drugs enter cancer cells
A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell.
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Study Shows How Anticancer Drug is Drawn into Cancer Cells
A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell.
Armed robbery in Revesby6d
Outside-In Signaling Shows Route Into Cancer Cells
X-dimer. The researchers found that when the anti-cancer antibody binds to P-cadherin, it locks it into the X-dimer form. The stable X-form then triggers a chemical signal that causes that patch of ...
UCD: Outside-in signaling shows route into cancer cells
A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals ...
Frontiers6d
T-CAST: An optimized CAST-Seq pipeline for TALEN confirms superior safety and efficacy of obligate-heterodimeric scaffolds
Each subunit of the dimer consists of a DNA-binding domain composed of an array of TALE repeats fused to the catalytically active portion of the FokI endonuclease. Upon DNA-binding of both TALEN arms ...