Hosted on MSN1mon
Scientists uncover rapid-acting, low-side-effect antidepressant target
The delta opioid receptor (DOP) plays a key role in mood ... The mechanistic (or mammalian) target of rapamycin (mTOR) signaling pathway, implicated in rapid antidepressant effects, was ...
The EMBO Journal22h
Modulation of tumor inflammatory signaling and drug sensitivity by CMTM4
Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...
Medscape14d
Management of Neuroendocrine Tumors: Current and Future Therapies
mTOR and tyrosine kinase inhibitors may play an increasing role in the management of well-differentiated neuroendocrine tumors in the future. Peptide receptor radiotherapy is a new treatment ...
Medscape5d
Targeting the Cancer Kinome Through Polypharmacology
and VEGF receptor 2 (VEGFR2)), the kinases in the MAPK pathway (for example, BRAF, MEK1 and MEK2) and the kinases in the PI3K pathway (for example, PIK3CA, Akt and mTOR). These three groups of ...
EurekAlert!1mon
Delta opioid receptor agonists exert antidepressant effects via the mTOR–PI3K signaling pathway (IMAGE)
Researchers from Tokyo University of Science uncover cellular and molecular mechanisms underlying the antidepressant-like effects of the delta opioid receptor agonists, paving the way for its ...
News Medical1mon
Uncovering the neurobiological mechanisms of delta opioid receptor agonists
The delta opioid receptor (DOP) plays a key role in mood ... The mechanistic (or mammalian) target of rapamycin (mTOR) signaling pathway, implicated in rapid antidepressant effects, was ...