Here we describe a mouse Fc receptor, designated Fcα/μR ... Fcα/μR also mediated primary B lymphocyte endocytosis of IgM-coated Staphylococcus aureus. Thus, Fcα/μR is involved in the ...

Reduced receptor-mediated LDL endocytosis causing raised blood LDL cholesterol (LDL-C) is the main defect, but other abnormalities due to lack of LDL receptors include altered hepatic cholesterol ...

Although NMDAR-LTD and mGluR-LTD involve distinct receptors and signalling mechanisms, some types of LTD require synergistic interactions between the two receptor subtypes 28. In the perirhinal ...

It is closely associated with tumorigenesis and drug resistance, making it a potential target for oncology drug development. To date, no ROR1-targeting drugs have been marketed. BR111 utilizes ...

This manuscript explores the role that WNT proteins play in receptor internalization ... Wnt proteins are required for ZNRF3/RNF43 mediated endocytosis and degradation of FZD receptors and this ...

fast endophilin-mediated endocytosis; CLIC/GEEC, clathrin-independent carriers/GPI-AP enriched early endosomal compartment; LRP2, low density lipoprotein receptor-related protein 2 (also known as ...

CFP1-deficient mice were more susceptible to bacterial infection due to the decreased expression of Csf2rα, a subunit of the GM-CSF receptor essential for inflammation ... host defense against ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Study of 2.4 million participants reveals potential advantages for cardiometabolic and psychiatric conditions alongside increased risks of gastrointestinal and musculoskeletal issues Study ...

The title and the abstract form the gateway to a study, and a well-defined combination rolls out the red carpet for the audience. The ability to write a good abstract is therefore an important skill, ...

Qatar, which mediated the agreement, said the cease-fire deal was set to begin at 8:30 a.m. local time on Sunday. By Aaron BoxermanRawan Sheikh Ahmad and Alan Yuhas Aaron Boxerman reported from ...

Vagally mediated atrioventricular (AV) block is defined as a paroxysmal AV block, localised within the AV node, associated with slowing of the sinus rate. All types of second-degree AV block, ...