A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell.
A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals ...
Merck Sharp & Dohme LLC has identified targeted activator of cell kill (TACK) compounds acting as Gag polyprotein (HIV-1)/protein Pol dimerization inducers reported to be useful for the treatment of ...
A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell.
A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...
Thurner syndrome (MTS) is a clinicopathological condition where the left common iliac vein is compressed by the overlying right common iliac artery, potentially leading to deep vein thrombosis (DVT) ...
We report that FHR-B is a dimeric protein resembling human FHR-1, FHR-2 and FHR-5, but involving a different dimerization domain with distinct structural and functional characteristics. Our studies ...
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Live your life healthier and happier with our free weekly Living Well newsletter As one of the three main macronutrients (along with fat and carbohydrates), protein is essential for promoting ...
We synthesized a geranyl dimer that binds to the central pocket with micromolar affinity, and dimeric peptides that bind the spike-tip pocket with sub-micromolar affinity. Cryo-electron microscopy ...