Ideaya is financially strong, with $1.2 billion in cash reserves, sufficient to fund operations into at least 2028. Click ...

Previous work has shown that the protein kinase C (PKC)–modulating drug bryostatin ... downregulating proinflammatory pathways and promoting regenerative and protective programs.

In contrast, when MnSOD transgenic mice are made diabetic, there is no activation of any of the four pathways. In endothelial cells, PKC also activates nuclear factor κB (NFκB), a transcription ...

Many cellular processes therefore rely on PKC, but many are also involved with ... agent”, which basically kickstarts certain pathways in latent cells infected by the HIV virus.

Nature 414:813-820, 2001. Consequences of hyperglycemia-induced activation of PKC. Hyperglycemia increases flux through the hexosamine pathway. From Brownlee M: Biochemistry and molecular cell ...

A compound with the unpresuming designation of EBC-46 has made a splash in recent years for its cancer-fighting prowess. Now ...

Notch signaling has been identified as a key regulatory pathway in patterning the endocardium through ... which activated mTORC2 and PKC and promoted Notch1 cleavage even in the absence of strong ...

To answer this question, the authors use a combination of in vivo and ex vivo experiments to demonstrate the critical role of hemodynamic forces on Notch1 activation and provide strong evidence for a ...

Detailed price information for Windtree Therapeutics Inc (WINT-Q) from The Globe and Mail including charting and trades.