Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal-regulated ... 2 and 3, PDGF receptors α and β, RET, Flt3, c-KIT and the RAF kinase and MAPK pathways.

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...

The brain of humans and other animals is known to contribute to the protection of the body from infections. Past studies have ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

Scientists uncover an enzyme that boosts cancer cell metabolism to fuel growth. The enzyme, GUK1, supports metabolism in cancer cells to help tumors grow.

This study presents solid evidence for distinct neurotransmitter release modalities between two subclasses of dopaminergic neurons in the olfactory bulb, highlighting an important finding that ...

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[19] Potentially important platelet mediators include platelet-derived growth factor (PDGF), TGF-beta 1, and epidermal growth factor (EGF). Fibrogenesis. Increased matrix production is the most ...

Day of Atonement; the scapegoat; the eating of blood forbidden; civil and religious laws; immorality forbidden We should also forgive and choose not to remember offenses against ourselves or others.