Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

Endometriosis, a prevalent gynecological condition, is characterized by the growth of endometrial-like tissues outside the ...

Acute pancreatitis (AP) is a gastrointestinal disorder characterized by inflammation and necrosis of the pancreatic acinar cells. Mitochondrial homeostasis is key to energy metabolism and redox ...

Mitoribosomes are present in the mitochondria of all eukaryotic cells. Their function is to allow the translation of mitochondrial mRNA that exclusively encodes components of the oxidative ...

BOSTON--(BUSINESS WIRE)--BPGbio, Inc., a leading biology-first, AI-powered clinical-stage biopharma company focused on mitochondrial biology and protein homeostasis, today announced the ...

Figure 2. Top 50 canonical pathways identified by IPA. As shown in Figure 2, among the top dysregulated pathways are mitochondria dysfunction and oxidative phosphorylation. These pathways are ...

However, the profound metabolic changes to mitochondria also render these organelles more sensitive to damage and place them precariously close to excess mitophagic activation. This review discusses ...

Elevating the oxidative stress by paraquat injection remarkably inhibited the long-distance flight of gregarious locusts. In respective crowding and isolation treatments, energy metabolic profiles and ...