Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

Cyanobacteria began contributing oxygen to Earth's mostly noxious atmosphere more than 2 billion years ago. The photosystem ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

Oxidative stress, an imbalance between the production of reactive oxygen species (ROS) and the ability to neutralize them ...

Acute pancreatitis (AP) is a gastrointestinal disorder characterized by inflammation and necrosis of the pancreatic acinar cells. Mitochondrial homeostasis is key to energy metabolism and redox ...

Mitoribosomes are present in the mitochondria of all eukaryotic cells. Their function is to allow the translation of mitochondrial mRNA that exclusively encodes components of the oxidative ...

Figure 2. Top 50 canonical pathways identified by IPA. As shown in Figure 2, among the top dysregulated pathways are mitochondria dysfunction and oxidative phosphorylation. These pathways are ...

and oxidative phosphorylation. The administration of exogenous AM2 alleviated heart failure following transverse aortic constriction. AM2 crucially regulates mitochondrial functions associated with ...

It then very quickly forms a complex with the two components of the enzyme nitrogenase, which protects them from oxidative damage. In this process, the activated Shethna protein II binds the much ...