Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers ...

Get Instant Summarized Text (Gist) Microglia, brain-resident immune cells, can be reprogrammed to combat melanoma brain metastases by blocking the Rela/NF-κB signaling pathway. This reprogramming ...

Brain metastases from prostate cancer (PC) seem to be more frequent than in the past, possibly because advances in the treatment of patients with castration-resistant PC have prolonged their survival.

Get Instant Summarized Text (Gist) Metastatic brain cancer should be recognized as a distinct central nervous system (CNS) disease due to its unique molecular, genetic, and microenvironmental ...

and specifically in the HER2-positive breast cancer brain metastasis, we observed that the presence of PIK3CA mutations, in fact, were linked to a worse prognosis. So a worse overall survival from ...

A recent Tampa, Fla.-based Moffitt Cancer Center study found that up to 25% of patients with stage 4 breast cancer may develop asymptomatic brain metastasis. The study, published Jan. 24 in Neuro ...

Researchers have found that the mutations driving it may stem from ... have been working to better understand what drives melanoma brain metastasis. They now report on the identification of ...

Feb. 4, 2025 — A research team has identified a critical event driving tumor growth in a type of medulloblastoma -- and a way to block ... Routine Brain MRI Screening in Asymptomatic Late Stage ...

Opens in a new tab or window A fourth of patients with metastatic breast cancer had asymptomatic brain metastases detected within 6 months after enrolling in a study of MRI-based surveillance.

The combination of brain radiotherapy and chemoimmunotherapy “resulted in promising intracranial and systemic anti-tumor activity, with a manageable safety profile,” researchers wrote.

A new study led by researchers at Moffitt Cancer Center shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed.