If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin ...

Cells have proteins called receptors ... Different receptors are specific for different molecules. Dopamine receptors bind dopamine, insulin receptors bind insulin, nerve growth factor receptors ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

"Rising ceramides in the cell are responsible for inflammation, insulin resistance ... PAQR4, a receptor in the same protein family, has an extremely similar structure; however, its function ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

The German team “serendipitously” identified a link between the activation of G-protein coupled receptors and cAMP formation, where the latter inhibits insulin signaling. “Obese mice that ...

Consomatin G1’s protein structure provides ... Safavi-Hemami’s previous venom insulin work, could help researchers design potential therapeutics. For instance, some neuroendocrine tumors predominantly ...