Introduction Definition of Peptides Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2 to ...

Peptides have gained significant attention in research due to their possible role in regulating various physiological ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin ...

The German team “serendipitously” identified a link between the activation of G-protein coupled receptors and cAMP formation, where the latter inhibits insulin signaling. “Obese mice that ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

Vimentin is a type III intermediate filament (IF) protein normally expressed in cells that develop into connective tissue, ...

A new study published in Biochemistry sheds light on how bacteria regulate their genes, challenging long-held assumptions ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Protein design (or protein engineering ... computational design of miniprotein binders of the pattern recognition receptor TLR3. When oligomerized, the miniprotein binders induce TLR3 signaling ...