The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...

A team of researchers from the Keck School of Medicine of USC has unlocked the details of a cellular pathway that triggers ...

If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin ...

Taking prednisone can make the liver resistant to insulin, raising blood sugar levels and potentially leading to steroid-induced diabetes. Steroids may also worsen existing diabetes symptoms.

We are aware of reports regarding supply issues of insulin in the UK. Some of these reports are of insulins that are being discontinued and some are where there is a temporary shortage. Here’s the ...

Insulin allows cells to absorb and use glucose. In people with insulin resistance, the cells are unable to use insulin effectively. Insulin resistance occurs when cells in the body do not respond ...

IGF1R can activate both PI3K and RTK pathways to promote tumor proliferation and invasion (Guan et al., 2023). In the high endo-derived hypoxia score group, it might be considered to combine IGF1R ...

Prices for insulin, the essential drug for treating diabetes, have plummetted to their lowest levels in a decade following a rise in generic options. Insulin prices averaged 19 cents per unit as ...

We remain the only company investing in a comprehensive ecosystem of differentiated technology for intensive insulin patients that takes on more of the work of the diabetes management and takes it off ...

Based on the perceived low efficacy of current therapies targeted to FGFR2 in gastric cancer (GC), the authors investigate an approach which combines SHP2 inhibition with existing FGFR2 inhibitors.

Many drugs, including insulin, essentially became free. But the American Rescue Plan made a major change that hit drug companies with even larger penalties for raising prices. In January 2024 ...