Heterocyclic insulin-like growth factor 1 receptor (IGF-1R; CD221) inhibitors potentially useful for the treatment of thyroid-associated ophthalmopathy (Graves’ ophthalmopathy) have been disclosed in ...

Secondary lymphedema occurs when, after surgery or radiotherapy, the lymphatic system cannot drain interstitial fluid effectively, leading to inflammation and fluid accumulation in the limbs. Previous ...

Linsitinib, which is designed to inhibit the insulin-like growth factor-1 receptor (IGF-1R) target, has an established safety profile in 15 clinical trials in multiple disease areas in more than ...