Topline results were announced from a phase 2/3 trial evaluating linsitinib for the treatment of moderate to severe thyroid eye disease.

Anxiety disorders, characterized by an excessive apprehension about real or perceived threats and dysfunctional behaviors aimed at avoiding these threats, are among the most common mental health ...

We hypothesized that inhibition of IGF-I receptor expression in the psoriasis lesion would reverse psoriatic epidermal hyperplasia by slowing the rate of keratinocyte cell division. Here we report ...

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GDC 2025 has revealed the finalists for the 27th annual Independent Games Festival (IGF). From almost 500 entries, the jurors selected the finalists "after playing, discussing, and meticulously ...

Last year's defining indie smash hit, Balatro? Not nominated for the IGF grand prize. Animal Well, which turned damn near every games journalist into a tiresome obsessive? Not nominated for anything.

However, with the anti-IGF-1R antibody Tepezza showing the benefits of targeting the receptor in TED, Sling spied a chance to use linsitinib in the eye disease. The biotech launched with $35 ...

N=4 mice per group. 3.4 CV1574-1 showed prolonged IGF-1 receptor activation in vitro Finally, we aimed to investigate the molecular mechanisms by which cartilage-targeting could enhance IGF-1 ...

Insulin-like growth factor 1, also known as IGF-1, is a crucial hormone that significantly affects muscle development and rejuvenation. This hormone is generated by the liver in response to the ...