Winged helix (wH) domains, also termed winged helix-turn-helix ... which cooperate to position an endonuclease dimer for a double strand (ds) cut in the DNA. Fully modified = M+ top/M+ bottom = M+/M+.

DNA (deoxyribonucleic acid), the molecular "blueprint" carrying the genetic instructions that influence the growth, ...

The platform enables direct, unbiased genome-wide identification and quantification of the exact position of double strand DNA breaks in edited cells.

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...

HR mechanisms generally achieve accurate repair of DNA damage. Double-stranded breaks are repaired by HR or by end-joining mechanisms, which can be non-homologous. Broken replication forks with ...

One of the astronauts stranded on the International Space Station since last June explained in a new interview that she is struggling to remember what it feels like to walk and lie down.

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

The combined 2% rewards rate — 1% when you make a purchase and 1% when you pay it off — is among the best on any cash-back card, especially for an annual fee of $0. Many or all of the products ...