The basis of peptide vaccination is the observation that leukemia cells can act as antigen-presenting cells (APCs) that cleave endogenous leukemia antigens in their proteasome and present them on ...

The cell type, CD8+ cytotoxic T lymphocytes that express a transcription factor called ZNF683/Hobit at high levels, appear to coordinate with other immune cells to expand and attack leukemia cells. In ...

This review focus on updating and integrating findings on T lymphocyte signaling generated using global phosphoproteomics approaches, drawing attention on the biological relevance of the obtained data ...

Thus low concentrations of lymphocytes, suppressed natural immunity, suppressed lymphocyte proliferation, and suppressed levels of secretory IgA in saliva are found simultaneously with high levels of ...

NK cells, as opposed to T cells, do not induce graft-versus-host disease (GVHD), therefore treatment-related toxicity owing to allogeneic donor NK cell administration is minimal. Alloreactive NK ...