(A) Schematic of Srs2 protein domains, regulatory features, and mutations affecting each of its features. Cdk1 phosphorylation sites depicted here include T604, S698, S879, S893, S938, S950, and S965 ...

Here we address this question by examining regulatory elements of Srs2, such as its phosphorylation, sumoylation, and protein-interaction sites. Our genetic analyses and checkpoint level assessment ...

This study aims to evaluate the potential value of CDK1 and STAT1 in the diagnosis of AKI in this patient population. Methods: A retrospective analysis was conducted on adjacent tissue, cancerous and ...

Association between ctDNA levels, timing of blood collection, and overall survival in metastatic colorectal cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal Cancers ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The DNA-damaging agent Gemcitabine (GEM) is a ...

Reversible phosphorylation is the basis for signal transduction in eukaryotic cells, and this is tightly controlled by the complex interplay of kinases and phosphatases. Many malignancies are ...

Wintering Monarch butterflies (Danaus plexippus), Santa Cruz, California. Masses of migrants gather in eucalyptus groves to overwinter before returning north; their numbers have decreased as a ...

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...

Department of Chemistry, New Cornerstone Science Laboratory, Institute of Biomimetic Materials & Chemistry, Anhui Engineering Laboratory of Biomimetic Materials, Division of Nanomaterials & Chemistry, ...