Pancreatic blood vessel cell map reveals potential diabetes treatment pathways
The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...
Science Daily6d
Outside-in signaling shows a route into cancer cells
A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...
eLife6d
GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis
This important study investigates the function of a critical regulator of human early cardiac development. The convincing examination of GATA6 function is thorough and well-executed. The study will be ...
Brain cells mimic muscle signaling to enhance learning and memory
This influx of calcium at the contact site attracts and activates a kinase called CaMKII, a protein known to be important in ...
Science Daily1d
From muscle to memory: New research uses clues from the body to understand signaling in the brain
New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals that make muscles contract are also responsible for transmitting signals in ...
eLife1d
Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of Osteoarthritis
This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...
The EMBO Journal5d
Editorial Teams
Deniz received her PhD from the University of Heidelberg. During her PhD work in the laboratory of Aurelio Teleman at the DKFZ, she uncovered a dedicated signaling pathway through which stearic acid ...