In MYCN-amplified NB cells, the half-life of N-Myc is significantly prolonged due to binding and stabilization by Aurora kinase A (Aurora-A; elevated in NB), resulting in increased steady-state ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

Puma Biotechnology will issue its 4Q and full year 2024 results on Feb. 27 and follow with a conference call at 1:30 p.m.

Puma Biotechnology, Inc. (NASDAQ: PBYI), a biopharmaceutical company, announced that on February 4, 2025, the Compensation ...

1Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 2The University of Texas MD Anderson Cancer Center, UTHealth Houston Graduate ...

This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...

This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...

Members of the NIMA-related kinases family (NEK proteins) are, judging by their complexity, close to vertebrates, whereas the complexity of Polo and Aurora mitotic kinase families are close to those ...

Aurora Innovation's pivot to autonomous trucking with a DaaS model is poised to capitalize on the trucking industry's driver shortage, offering significant cost savings and profitability ...