The Scientist7mon
A Protein-Sensing Molecular Switch Alters Facial Features
3 To study how mTORC1 signaling influenced facial development after the initial feature formation, the researchers activated mTORC1 in cartilage progenitor cells in the KO mice models at E12.5 and saw ...
Hosted on MSN11mon
Enzyme checkpoint identified in tumor-associated macrophages
The research team was able to demonstrate that the PHGDH-mediated serine metabolic pathway plays a crucial role in processes associated with the regulation of the mTORC1 signaling pathway (key ...
Hosted on MSN28d
Scientists uncover rapid-acting, low-side-effect antidepressant target
More information: Toshinori Yoshioka et al, Delta opioid receptor agonists activate PI3K–mTORC1 signaling in parvalbumin-positive interneurons in mouse infralimbic prefrontal cortex to exert ...
Medical Xpress20d
Discovery reveals birth's impact on neural stem cell maintenance
They showed that RG transiently enter a neurogenic state via mTORC1 signaling in preterm birth mice. However, they also found that neurogenesis at the young-adult stage was decreased due to ...