Ubiquitin and the Biology of the Cell, as the editors note, is published 10 years after the first book on ubiquitin appeared and 23 years after the first biochemical description of this ubiquitous ...

Modification with Nedd8 of cullin 1 within the SCF–Skp2 complex has been proposed to be required for ubiquitination of the cell-cycle inhibitor p27 Kip1 (ref. 11). Figure 2: Destructive pathways ...