Oncolytic viruses (OVs) are viruses that infect and kill cancer cells while sparing healthy tissue, making them a promising therapeutic option in cancer ...

Oncolytic viruses—viruses that selectively target ... The team genetically engineered an adenovirus (a type of virus typically associated with common colds) to deliver a modified version of ...

a whole panel of oncolytic viruses with a variety of antitumour functions could be available in the future, from which a combination of appropriate viruses can be selected according to the type ...

"It also strongly supports emerging evidence that there may be biological differences in patients more likely to respond to this kind of immunotherapy—oncolytic viruses—versus other types that ...

Cold Genesys is a clinical-stage company developing an oncolytic virus (CG0070) for multiple tumor types as a single agent and in combination with immune system checkpoint inhibitors. Already with ...

Delytact (teserpaturev) is a genetically engineered oncolytic herpes simplex virus type 1 (HSV-1) that was approved for marketing in Japan earlier this year, and received pricing approval in ...

Oncolytic viruses thereby directly kill cancer cells and cause the release of tumor-associated antigens that enable the immune system to recognize a cancer type and develop long-term memory ...

Oncolytic viruses are therapeutic agents used for in situ immunization in cancer immunotherapy. Unfortunately, its efficacy is particularly limited in solid tumors expressing stimulator of interferon ...

Defects in activation of antiviral signaling pathways Defects in activation of RIG-I, IRF-3 and IRF-7 [46,85,86,88] Defects in type I interferon ... Newcastle disease virus; OS: Overall survival ...

They confirmed this by identifying choroid plexus cells, the cell type that secretes cerebrospinal ... Could be used to treat brain tumors Oncolytic viruses are used as an immunotherapy against ...

They confirmed this by identifying choroid plexus cells, the cell type that secretes cerebrospinal ... Could be used to treat brain tumours Oncolytic viruses are used as an immunotherapy against ...

This comprehensive whitepaper analyzes the evolving landscape of oncolytic virus therapies (OVT), providing critical insights into this transformative approach to cancer treatment.