Researchers discovered a molecular timer that gets activated in the first days of pregnancy and influences when mice give ...

The rate of biological aging indicates the discrepancy between chronological age and biological age, that is, whether a ...

DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...

The addition or removal of methyl groups from DNA is one of the most studied epigenetic modifications. Without changing the genomic sequence, it changes the activity of genes, because it's harder ...

However, DNMT1 rapidly scans DNA and deposits methyl groups on newly synthesized DNA, opposite methyl groups present on the old DNA strand. This results in faithful replication of methylation ...

KUNMING -- Chinese researchers have recently discovered that unique DNA methylation characteristics in long-lived men grant ...

Humans do not always age biologically at the same rate as their chronological age. Faster biological aging compared to chronological age has been linked to higher risks of disease and mortality.

For instance, in normal, healthy mice, the agouti genes are kept in the "off" position by the epigenome, which attaches methyl groups to the corresponding regions of DNA, resulting in the DNA's ...

Humans do not always age biologically at the same rate as their chronological age. Faster biological aging compared to chronological age has been linked to higher risks of disease and mortality.