Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers ...

Get Instant Summarized Text (Gist) Microglia, brain-resident immune cells, can be reprogrammed to combat melanoma brain metastases by blocking the Rela/NF-κB signaling pathway. This reprogramming ...

Patients with ERBB2-positive breast cancer and CNS-only metastasis are at a high risk for CNS-related death but have longer overall survival than those with concomitant extracranial metastases.

and specifically in the HER2-positive breast cancer brain metastasis, we observed that the presence of PIK3CA mutations, in fact, were linked to a worse prognosis. So a worse overall survival from ...

Get Instant Summarized Text (Gist) Metastatic brain cancer should be recognized as a distinct central nervous system (CNS) disease due to its unique molecular, genetic, and microenvironmental ...

A recent Tampa, Fla.-based Moffitt Cancer Center study found that up to 25% of patients with stage 4 breast cancer may develop asymptomatic brain metastasis. The study, published Jan. 24 in Neuro ...

Feb. 4, 2025 — A research team has identified a critical event driving tumor growth in a type of medulloblastoma -- and a way to block ... Routine Brain MRI Screening in Asymptomatic Late Stage ...

Opens in a new tab or window A fourth of patients with metastatic breast cancer had asymptomatic brain metastases detected within 6 months after enrolling in a study of MRI-based surveillance.

A new study led by researchers at Moffitt Cancer Center shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed.

The combination of brain radiotherapy and chemoimmunotherapy “resulted in promising intracranial and systemic anti-tumor activity, with a manageable safety profile,” researchers wrote.

During a Case-Based Roundtable® event, Thach-Giao Truong, MD, discussed how data from the CheckMate-067 and RELATIVITY-047 ...