Insulin and the ... were to affect leptin signal transduction as well, and the previous discussion highlighting cross talk between leptin and insulin signaling pathways emphasizes the feasibility ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

and the IGF-1 (insulin-like growth factor) receptor, which is essential for the survival of many tumor types. Signal transduction companies currently face two key challenges: First, the pathways ...

Dopamine receptors bind dopamine, insulin receptors bind insulin ... These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing ...

Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in BMP2 signaling pathways," Cell, 85:489-500 ... is one thing that is known about the mechanisms that govern signal transduction, it ...

Insulin also has a role in the modulation of longevity, mediated via one of the insulin-like growth factor 1 receptor (IGF1-R) signal transduction pathways. The Caenorhabditis elegans IGF1-R homolog ...

Scientists have identified a novel enzyme, SNO-CoA-assisted nitrosylase (SCAN), which plays a crucial role in regulating insulin production ... parallels to other signal transduction processes ...

Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...

Thus, neuronal insulin-like signaling appears to be a key regulator of various essential functions in C. elegans, and the metabolic and reproductive defects induced by whole-body deletion of DAF-2 ...