If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

Cells have proteins called receptors ... Different receptors are specific for different molecules. Dopamine receptors bind dopamine, insulin receptors bind insulin, nerve growth factor receptors ...

The IGFBP7 protein helps control the availability of insulin-like growth factors (IGFs) in body fluids and tissues and increase or decrease the attachment (binding) of IGFs to other molecules called ...

"Rising ceramides in the cell are responsible for inflammation, insulin resistance ... PAQR4, a receptor in the same protein family, has an extremely similar structure; however, its function ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.

Consomatin G1’s protein structure provides ... Safavi-Hemami’s previous venom insulin work, could help researchers design potential therapeutics. For instance, some neuroendocrine tumors predominantly ...