C&EN3d
If insulin can’t get into tissues, it can’t act
If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin ...
Nature4y
G-Protein-Coupled Receptors, Pancreatic Islets, and Diabetes
Without supplemental insulin treatment ... and this hormone binds to glucagon receptors in the liver. This binding stimulates breakdown of glycogen and the release of glucose into the circulation.
News Medical on MSN14d
Unlocking the potential of receptor-based approaches in diabetes treatment
Announcing a new article publication for BIO Integration journal.   Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance ...
High levels of adrenomedullin found to promote obesity-associated insulin resistance
Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...
News Medical on MSN7d
A pathway that contributes to insulin resistance can be targeted, mouse study shows
The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...
GEN6d
Obesity-Linked Hormone Adrenomedullin Disrupts Insulin Signaling
Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.
Today's Dietitian magazine3d
What’s the Mechanism Behind Behavioral Side Effects of Weight Loss Drugs?
GLP1RA mimic the GLP-1 hormone in the body that helps control insulin and blood glucose levels and promotes feelings of satiety. GLP-1 binds to GLP1R on cells in the brain and pancreas.