and high-affinity IL-2 receptors, and they are expressed individually and variably on distinct cell types. PEG modification, IL-2 mutant design, fusion Fc, bispecific antibody design, combination ...
Anti-CD25 mAbs that selectively block IL-2 receptors (IL-2 receptor antagonists) on activated T helper cells are being used prophylactically as complementary immunosuppression with CsA and ...
Imsidolimab has successfully completed two global Phase 3 studies in Generalized Pustular Psoriasis <li /> Vanda expects to immediately ...
Investigative therapies to treat moderate to severe plaque psoriasis in clinical trials include several orally administered ...
Medpage Today on MSN6mon
IL-2 Receptor-Targeted Therapy Approved for Relapsed/Refractory CTCLThe therapy has a direct cytotoxic effect on tumor cells that express IL-2 receptors and depletes host Tregs to enhance ...
Medicenna's long-acting IL-2 Superkine, MDNA11, is a next-generation IL-2 with superior affinity toward CD122 (IL-2 receptor beta ... early-stage high-affinity IL-2β biased IL-2/IL-15 ...
Researchers have previously demonstrated antidepressant-like effects of delta opioid receptor ... potential of DOP agonists. Additionally, KNT-127's application to isolated IL-PFC brain tissue ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback