We hypothesized that inhibition of IGF-I receptor expression in the psoriasis lesion would reverse psoriatic epidermal hyperplasia by slowing the rate of keratinocyte cell division. Here we report ...
Anxiety disorders, characterized by an excessive apprehension about real or perceived threats and dysfunctional behaviors aimed at avoiding these threats, are among the most common mental health ...
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New Scientist on MSNRare mutation that causes short stature may shed light on ageingPeople with a rare genetic mutation that causes short stature and may also make them live longer are helping shed light on ...
Linsitinib is an oral small molecule that inhibits the activity of insulin-like growth factor-1 receptor (IGF-1R). It is believed that inhibition of IGF-1R may help reduce orbital inflammation and ...
Linsitinib, which is designed to inhibit the insulin-like growth factor-1 receptor (IGF-1R) target, has an established safety profile in 15 clinical trials in multiple disease areas in more than ...
However, with the anti-IGF-1R antibody Tepezza showing the benefits of targeting the receptor in TED, Sling spied a chance to use linsitinib in the eye disease. The biotech launched with $35 ...
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