Han, R.J. Ulevitch, R.J. Davis, "Pro-inflammatory cytokines and environmental stress cause p38 ... Howard Hughes Medical Institute. The signal transduction pathways of mitogen-activated protein (MAP) ...

Signal transduction describes the process of conversion of external signals, such as hormones, growth factors, neurotransmitters, and cytokines, to a specific internal cellular response ...

Investigation of small molecular therapies that inhibit signal transduction resulting in reduced inflammatory cytokine production has been ongoing for the last decade. Original efforts targeting ...

Aclaris Therapeutics (ACRS) announced the availability of a new publication describing properties of Aclaris Therapeutics’ ATI-2138, a novel ...

Data Generated to Date Support Potential for Aclaris’ ATI-2138 to Impact Several Human Inflammatory Diseases -WAYNE, Pa., Feb. 12, 2025 ...

and uncoupling of ligand/receptor pairing from signal transduction. Insight into cytokine balance is leading to novel therapeutic approaches particularly in autoimmune conditions, which are ...

Aclaris Therapeutics, Inc. (NASDAQ: ACRS) has announced significant findings about ATI-2138, a novel investigational drug ...

The findings highlight the significance of frequency-selective cellular responses in developmental biology, providing valuable insights into the intercellular signal transduction mechanisms.

Interleukin-3 (IL-3) is a cytokine that regulates hemopoiesis ... "I wanted to find out what the next step in the signal-transduction cascade was," she states. "How does receptor activation lead ...