Primary central nervous system lymphoma (PCNSL) is a rare disease that is managed differently from other primary brain tumors and other types of systemic lymphomas. The use of high-dose ...

Background: Methotrexate-based chemotherapy is the first-line treatment for patients with primary central nervous system lymphoma (PCNSL); however, in most cases this disease remains incurable.

However, since this lymphoma originates primarily and is located in the central nervous system, usually in the brain, it's also considered a brain tumor. It occurs due to the uncontrolled ...

Medically reviewed by Doru Paul, MD Lymphoma symptoms can vary depending on the type of lymphoma you have and the location of the malignancy (cancer). With both Hodgkin lymphoma (HL) and non-Hodgkin ...

A group led by the Department of Neurosurgery, Brain Research Institute, Niigata University succeeded in the diagnosis of ...

Patients with lymphoma or leukemia with methotrexate-induced acute kidney injury experienced improved renal outcomes ...

Between November 1999 and June 2002, 72 patients of median age 44 years (range 8–72 years) with various central nervous system malignancies ... patients (52%). All lymphoma patients responded ...

Diagnosis of Leptomeningeal Disease in Diffuse Midline Gliomas by Detection of H3F3A K27M Mutation in Circulating Tumor DNA ...

A group at Niigata University succeeded in the early diagnosis of leptomeningeal disease in H3K27M-mutant diffuse midline ...