Originally, cell cycle studies were the preserve of microscopy ... Current research has identified a large number of signaling pathways, many comprising several genes, involved in regulating ...

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

According to this model, mutant KRAS is able to hydrolyze guanosine triphosphate (GTP) and cycle ... effector pathway in pancreatic ductal adenocarcinoma (PDAC) models, with its signaling ...