A new study published in Biochemistry sheds light on how bacteria regulate their genes, challenging long-held assumptions ...

A new study, "Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein" published in Biochemistry, provides key insights into how bacterial cAMP receptor proteins (CRPs) ...

A new study led by Dr. Rodrigo Maillard at Georgetown University, “Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein through Structural Homology,” published in ...

You have full access to this article via your institution. In summary, our data provide evidence that most cAMP and cGMP analogs have multiple targets. Therefore, interpretation of any effects ...

These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing multiple intracellular signals for every one receptor that is bound.

Credit: Dr. Tetsuya Muramoto The study revealed the mechanisms by which periodic intracellular cAMP signal frequencies regulate transcription factor shuttling between the nucleus and cytoplasm and ...