Urinary Sodium and Potassium, and Aldosterone Secretion before and after Guanethidine Treatment, and Six Months after Surgical Removal of the Tumor (the Stippled Areas Represent the Normal Ranges).

Primary aldosteronism treatment response was associated with higher plasma renin activity and serum potassium levels and lower aldosterone.

Potassium and renal function must be routinely assessed to minimize the risk of life-threatening hyperkalemia. This review discusses the role of aldosterone antagonists in the treatment of heart ...

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally ...

Through this mechanism, diuretics may increase ... and impairing arterial compliance. Aldosterone also promotes potassium and magnesium depletion, which is potentially proarrhythmic.

Elevated aldosterone stimulates sodium reabsorption in the cortical collecting duct as a backup mechanism of maintaining homeostasis. This mechanism results in increased potassium and hydrogen ion ...