Stoke-on-Trent is a city and unitary authority area in Staffordshire, England. It has an estimated population of 259,965, making it the lar…Stoke-on-Trent is a city and unitary authority area in Staffordshire, England. It has an estimated population of 259,965, making it the largest settlement in Staffordshire and one of the largest cities of the Midlands. Stoke is surrounded by the towns of Newcastle-under-Lyme, Alsager, Kidsgrove and Biddulph, which form a conurbation around the city.